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What is Tramadol?

Tramadol is a synthetic opioid analgesic, primarily used in the medical field for the treatment of moderate to severe pain. It functions both as a typical opioid and as a serotonin-norepinephrine reuptake inhibitor (SNRI). Tramadol's dual mechanism of action makes it unique among opioids, as it not only alters the perception of pain in the body by binding to the mu-opioid receptors but also affects neurotransmitters involved in pain modulation.




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Developed in the 1960s by German scientists, tramadol was introduced into the market as 'Tramal.' It gained approval for medical use in the United States and the United Kingdom in the mid-1990s. Since then, tramadol has been widely prescribed for various pain-related conditions, including postoperative pain, neuropathic pain, and certain cases of chronic pain disorders such as fibromyalgia, though it's not FDA-approved for this particular condition.



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